Involvement of the nervous system is one of the most dreaded complications of systemic cancer, striking fear into the hearts of patients and their loved ones and often causing considerable trepidation in their physicians. This issue is still prevalent despite numerous advances in cancer therapy over the past 60 years. Neurologists, medical oncologists, radiation oncologists, neurosurgeons, and neuro-oncologists in practice need to be aware of the broad spectrum of neurological complications of cancer that can occur in their patients and be well versed in the newest approaches to diagnosis and treatment. This is critical since rapid diagnosis and institution of appropriate therapy may minimize neurological injury and preserve quality of life.
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