دانلود کتاب میکروبیوم روده در سلامت و بیماری: یک کتاب درسی – ویرایش دوم

In 2013, the German Research Foundation (DFG) began funding the Priority Program (SPP) 1656 entitled “Intestinal Microbiota” and thereby consolidated a concerted action of the German Society of Hygiene and Medical Microbiology (DGHM) to support microbiome research in Germany. An interdisciplinary network of scientists, including microbiologists, gastroenterologists, immunologists, nutrition scientists, and physicians, worked together over the past 12 years to achieve novel insights into the role of the gut microbiome in health and diseases. Recent advances in this field stimulated the second generation of coordinated research yielding into microbiome-centered Collaborative Research Centers (CRCs) funded by the German Research Foundation (DFG), including CRC 1182 “Origin and function of Meta organisms” in Kiel, CRC 1371 “Microbiome Signatures – functional relevance in the digestive tract” at the Technical University of Munich, and SPP 2474 “Illuminating gene function in the human gut microbiome.” In addition, the German Excellence Strategy actively supports microbiome research through dedicated funding of Clusters of Excellence (“Controlling microbes to fight Infections” in Tübingen and “Balance of the microverse” in Jena) in understanding microbial communities and their impact on health and the environment. Beyond the numerous scientific accomplishments, the consortia made an effort to use their complementary expertise in educating the next generation of young researchers. Many colleagues contributed to the Second Edition of this book, providing a comprehensive reflection of cutting edge knowledge on the gut microbiome and its functions in human health and diseases, covering basic principles of the gut microbial ecosystem (the impact of diet on composition and metabolic activities as well as its evolution over time and life stages), its reciprocal interaction with the mucosal immune system, and the clinical implementation related to diagnosis and therapy. Considering the needs for a continuous education process of students and health professionals, the Second Edition of this book is supported by the CRC 1371 and provides a structured and modern overview about the methodologies applied as well as the scientific and clinical aspects of microbiome-host interactions, highlighting perspectives on historic developments and controversies in the field.