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Introduction to Drugs and Pregnancy

Approximately 3.5–5 percent of live-born infants have a birth defect when examined at birth or neonatally (Polifka and Friedman, 2002), and this is termed the background population risk for congenital anomalies. The prevalence of birth defects may normally be 8 percent, according to a British Columbia universal disease registry (Baird et al., 1989).