دانلود کتاب زیست‌ساخت در پزشکی بازساختی: فناوری‌های پایه، روش‌های نوظهور و کاربردها

Biofabrication appears to be ushering in a new era in regenerative medicine. What was once considered a distant dream is slowly becoming a tangible reality. Exciting developments are underway in the fabrication of functional living tissues or organs in the laboratory. The field of tissue engineering and regenerative medicine, which emerged in the early 1990s, has undergone a revolutionary transformation in the last decade, particularly driven by advancements in 3D bioprinting technology. Traditional biofabrication methods, which have led to some progress in the development of biomimetic tissues, are evolving into unconventional new hybrid approaches offering innovative solutions for creating scalable and multi-component hierarchical tissues. This book offers a journey into the fascinating world of biofabrication in regenerative medicine, reflecting years of research into advanced technologies and approaches, and the determined efforts to translate this knowledge into applications. Each chapter aims to provide a comprehensive understanding of the multifaceted aspects of this groundbreaking field. The first chapters of the volume cover the fundamentals of biofabrication strategies, the various types of biomaterials used, and the properties of bioinks. Next, smart materials that translate physical cues into cellular responses and neovascularization strategies are discussed. Subsequent chapters describe state-of-the-art developments in the biofabrication of various tissues, including skin, tendons, trachea, bone, skeletal muscle, blood vessels, and the eye. The final chapters address current approaches, namely, 3D-engineered platforms for disease modeling and the role of deep learning and artificial intelligence in biofabrication for regenerative medicine. I would like to extend my sincere thanks to Merry Stuber, senior editor of the Stem Cell Biology and Regenerative Medicine series, for her support throughout this work, and to the production team for their extraordinary dedication in bringing this volume to life. I also express my gratitude to all the valuable authors who have contributed their scientific perspectives and expertise to this volume.