دانلود کتاب کاربردهای عملی زیست شناسی محاسباتی و بیوانفورماتیک، شانزدهمین کنفرانس بین المللی (PACBB 2022)

The success of bioinformatics in recent years has been prompted by research in molecular biology and molecular medicine in several initiatives. These initiatives gave rise to an exponential increase in the volume and diversification of data, including nucleotide and protein sequences and annotations, high-throughput exper-imental data, biomedical literature, among many others. Systems biology is a related research area that has been replacing the reductionist view that dominated biology research in the last decades, requiring the coordinated efforts of biological researchers with those related to data analysis, mathematical modelling, computer simulation and optimization.

The accumulation and exploitation of large-scale databases prompt new compu-tational technology and for research into these issues. In this context, many widely successful computational models and tools used by biologists in these initiatives, such as clustering and classification methods for gene expression data, are based on computer science/artificial intelligence (CS/AI) techniques. In fact, these methods have been helping in tasks related to knowledge discovery, modelling and optimiza-tion tasks, aiming at the development of computational models so that the response of biological complex systems to any perturbation can be predicted. The 16th Interna-tional Conference on Practical Applications of Computational Biology & Bioinfor-matics (PACBB) aims to promote the interaction among the scientific community to discuss applications of CS/AI with an interdisciplinary character, exploring the inter-actions between sub-areas of CS/AI, bioinformatics, chemoinformatic and systems biology. The PACBB’22 technical programme includes ten papers of authors from many different countries (Bahrain, Canada, France, Italy, Portugal, Saudi Arabia, Spain and UK) and different subfields in bioinformatics and computational biology. All papers underwent a peer review selection: each paper was assessed by three different reviewers from an international panel composed of about 46 members from 11 countries. The quality of submissions was on average good, with an acceptance rate of approximately 60% (10 accepted papers from 15 submissions).