دانلود کتاب مکانیسم‌های سلولی و مولکولی در بیماری آلزایمر -درمان‌شناسی مکانیسم‌های سلولی، ویرایش اول

Alzheimer’s disease (AD) remains one of the most formidable neurodegenerative disorders, affecting millions worldwide. Despite extensive research, there is still much to uncover about the cellular mechanisms that underlie its pathology and drive disease progression. As the global population ages, the need for effective therapeutic strategies becomes increasingly urgent. This edited volume, Cellular and Molecular Mechanisms in Alzheimer’s Disease Therapeutics, aims to provide a detailed and up-to-date exploration of the cellular and molecular processes involved in AD, with an emphasis on their implications for therapeutic interventions. The book brings together contributions from leading experts in the field, offering a comprehensive understanding of how various cellular mechanisms, such as synaptic dysfunction, neuroinflammation, mitochondrial impairment, and protein aggregation contribute to the pathology of AD. We, as editors, Dr. Prashant Tiwari, Dr. Sunil Kumar Kadiri, and Dr. Kunjbihari Sulakhiya, have curated this volume to facilitate the integration of basic research and clinical application. By focusing on the cellular and molecular insights into AD, we hope to pave the way for novel therapeutic approaches that address the root causes of neurodegeneration. Special attention is given to the role of cellular stress responses, autophagy, tau and amyloid-beta pathology, and the emerging therapeutic potential of gene therapy, precision medicine, and immune modulation. The contributions in this volume reflect the latest advancements in the field, providing readers with a nuanced understanding of both established and cutting-edge therapeutic strategies aimed at combating AD. It is our hope that this book will serve as a valuable resource for researchers, clinicians, and students dedicated to understanding and treating AD. We are deeply grateful to all the authors who have contributed to this work, as well as to the team at Apple Academic Press for their support in bringing this project to fruition. Through the collaborative efforts of the scientific community, we remain hopeful that new breakthroughs will emerge that can halt, or even reverse, the devastating effects of AD.