دانلود کتاب درسی آسیب شناسی، ویرایش دوم، جلد دوم: آسیب شناسی سیستمیک و تشخیص مولکولی

Rudolph Virchow (1821–1902) is the father of ‘Cellular Pathology’ in terms of the dysfunction of cells. Many pathologic observations are being published in the Textbooks and Journals by great authors across world. Their outstanding contribution in the field of medical practice and education has been a great source of inspiration. Second Edition of Textbook of Pathology, extensively revised, updated with recent developments as needed and amended as per the ‘CompetencyBased Medical Education Curriculum’ is intended to provide undergraduate and postgraduate medical students with clear, and concise presentation of the pathologic basis of the human disorders. The field of pathology emerged from the application of the scientific method to study of nature, etiology, molecular mechanism, and interrelated anatomical, functional, clinical manifestations and consequences of human diseases through examination of blood and tissue specimens. The description of the human disorders evolved over time from gross morphology observation to the histologic examination of the diseased tissues based on the specific immunohistochemical stains, immunofluorescence microscopy, immunophenotyping, fluorescence in situ hybridization, molecular diagnostics and more recently to ultrastructural analysis of the disease with the advent of electron microscope. Thus, molecular pathology as a discipline represents the complementary intersection of medicine and basic science discoveries and the basis for the development of new strategies for disease pervention. Textbook of Pathology has three sections: (i) General Pathology, (ii) Hematology including chapter on ‘Blood Banking and Transfusion Practices’, and (iii) Systemic Pathology and Molecular Diagnostics. This textbook contains approximately 1901 highresolution colored figures and 1719 tables, which would complement quick revision of the chapters. It provides comprehensive coverage of etiology, molecular pathogenesis of human disorders, clinical manifestations, clinicopathological correlation and diagnostic approach. Pathology is the fundamental bridging discipline linking the basic biomedical sciences to clinical medicine. Therefore, our basic aim is for our undergraduate as well as postgraduate medical students to use their knowledge of pathology to become scientifically gorunded effective clinicians and healthcare professionals. We hope that Textbook of Pathology will accomplish its purpose of providing medical students and researchers with indepth coverage of molecular basis of a wide spectrum of human disorders in the context of understanding the molecular mechanisms of the disease and advancing the theory and practice of molecular medicine