Metabolic diseases, such as diabetes and others associated with the current obesity crisis, have thrust metabolism into the forefront of popular thinking. In many ways, metabolism is the central science of biochemistry. This is the view I have adopted as the core concept of this textbook. Having a research background in metabolism, a long-standing interest in the fundamental topics of biochemistry – including kinetics and thermodynamics – and having taught a one-semester biochemistry course for over 25 years, I have long wanted to write a book that reflects the whole of the subject with the unifying theme of metabolism.
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