دانلود کتاب نشانگرهای زیستی به عنوان کشف داروی گیاهی هدفمند

Conventional medications have limited efficacy and high toxicity. Herbal drug discovery based on biomarkers emerging as complementary and alternative medicine have tremendous potential with wide structural diversity, which is not usually seen with conventional/synthetic drug molecules. Recognition of various herbal constituents such as terpenoids, fatty acids, flavonoids, and steroids has been well explored in the management/treatment of various disorders. These agents target various biomarkers such as nitric oxide (NO),  cytokines, chemokines, adhesion molecules, NF-kβ, lipoxygenase (LOX),  and arachidonic acid (AA).  The second part of this book is on nanomedicine; the word nano is a buzz word today in the era of the twenty-first century. With the advent of nanotechnology, the world has witnessed a significant momentum in exploring the precepts and perspectives of this evolutionary technology for diverse applications in various fields.  Importantly, nanotechnology applications in the healthcare sector have benefited a lot for their application in providing benefits to the patient community by serving unmet medical needs. In this regard, the physicochemical properties of herbal drugs and vehicles are considered to be highly significant for drug absorption. These factors restrict the site-specific action and limited penetration through site. To avoid these shortcomings, nano/ submicromedicines have been developed to improve the absorption of such bioactives via optimizing the physicochemical properties of herbal drugs, vehicles, and barriers.