دانلود کتاب اصول، فناوری‌ها و نوآوری‌های نوظهور حسگرهای زیستی

This textbook provides a comprehensive introduction to biosensors, integrating foundational principles, measurement methodologies, and modern technological advancements with a particular focus on biomedical and analytical applications. It is intended for students, researchers, and professionals in biomedical engineering, analytical chemistry, biotechnology, and sensor technology. This book begins with an overview of biosensors, outlining their historical evolution, fundamental components, and classification. It introduces the key elements of biosensor systems, including biorecognition mechanisms, transduction processes, and signal processing approaches, while emphasizing the interplay between biological specificity and physicochemical detection methods. Subsequent sections present the theoretical foundations of biosensors, covering static and dynamic sensor characteristics, measurement errors, and uncertainty analysis. A dedicated chapter introduces the ISO Guide to the Expression of Uncertainty in Measurement (ISO GUM), providing structured approaches to uncertainty budgeting and traceability in biosensor performance evaluation. This book then explores the major categories of biosensors, electrochemical, optical, impedance, acoustic, and field-effect transistor (FET)-based systems, detailing their operational principles, technical characteristics, and representative applications. The discussion extends to immunosensors and nanomaterial-enhanced platforms, reflecting recent trends in sensitivity improvement, miniaturization, and real time data acquisition. A separate section is devoted to biomedical and healthcare applications, highlighting the use of biosensors in disease diagnostics, drug monitoring, wearable health systems, and point-of-care technologies. The integration of biosensors with artificial intelligence, Internet of Things (IoT) frameworks, and lab-on-a-chip systems is examined, emphasizing their potential in personalized and preventive medicine. The concluding chapters discuss future trends and challenges in biosensor development, including issues of biocompatibility, stability, regulatory compliance, and data-driven analytics. By combining theoretical rigor with practical insight, this textbook serves as an essential reference for understanding biosensors and their expanding role in modern biomedical engineering, healthcare, and analytical science.