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Many pathophysiology books have been written to address the informational needs of the medical community, but learners in allied health professional programs require an essential pathophysiology text geared specifically for these programs. Human Diseases, Sixth Edition is designed and specifically written for learners in health care programs pursuing careers as allied health professionals, including but not limited to medical assistants, medical coders, surgical technologists, respiratory therapist assistants, physical therapist assistants, radiologic technologists, medical transcriptionists, emergency medical technicians, nursing assistants. The book is intended to meet the needs of learners enrolled in an allied health career program as well as serve as a valuable resource for health care professionals on the job. It is also ideal as a resource on basic diseases by anyone within the medical arena or individuals interested in human diseases. Current information for this book was based on the authors’ own experiences and research sought from current literature, books, Internet resources, and physician consultations. Students will understand this text best if a basic medical terminology or anatomy and physiology course has been completed before this course of study. However, this book is designed to make difficult pathophysiology concepts easier to understand by using a consistent organization, and including pronunciations, boxed features, and full-color illustrations and photos of diseases and disorders. Organized into three units, the book begins with basic concepts of human diseases, introduces common diseases and disorders of the body systems, followed by genetic and developmental, childhood, and mental health diseases and disorders. Chapters progress through a basic review of anatomy and physiology before introducing the most common diseases related to each system and specialty area. Common diseases and disorders for each body system are presented consistently through a description of the disease or disorder, the etiology, symptoms, diagnosis, treatment, and prevention. Simulated real-world activities provide learners with hands-on experience applying key concepts learned in the chapters into practice. Several dilemmas immediately emerge when one considers writing a textbook for such a large and diverse audience as the health care field. Questions arise as to how much content to include, what to exclude, how detailed the content should be, and how to organize the content in the most understandable manner. Another common concern is the question of the appropriate reading level. In an attempt to resolve these dilemmas, it was decided to organize the book in such a way that blocks of material or even entire chapters could be omitted or covered in detail, depending on the format of the course and needs of the learner. At the same time, information on each disease is written in such a way that it can stand alone or be viewed as all inclusive. This concept allows the instructor, learner, or individual to select and study only those specific diseases or individual disease of interest. Not all health conditions are covered in the text, so the conditions chosen to be included are those that are most common, along with the new and emerging diseases. A few rare conditions are also included. Of the conditions chosen for the text, only general information is covered. The text is designed to be a basic overview of common diseases and disorders, not an in-depth study. Thus, the diseases presented are not described on a cellular physiological level, which would be too complex for the intended audience. The intention also was to keep the reading level of the text at an easyto- read basic level to promote understanding. We did not want to write beneath the level of the learner but, at the same time, felt that a difficult reading level would only increase the complexity of the material and thus fail to promote understanding of the subject matter.