دانلود کتاب ایمونولوژی محاسباتی

Computational Immunology: Applications highlights the different applications of computational techniques, statistical methods, and mathematical models in human health and disease, some of them being the most challenging problems in the world and in understanding of the immune biology of the invertebrates, being the most intriguing problems in biology. We discuss the application of different computational tools and mathematical models in predicting cell fate, one of the most intriguing questions in modern day biology.

In this volume, we discuss the diverse, integrated tools, techniques, and imaging interfaces that are helping in diagnosis and prognosis of disease. The major problems associated with end stage organ failure require organ transplantation. There are more patients in need of organs than there are available organs for transplantation, and most often it is not known that an organ is available, adding to the trauma and pain of the patients. Computational approaches have been used by the World Health Organization (WHO) to make a global knowledge base on transplantation (GKT), with information from different sources for organ, tissue, and cell donation and transplantation globally, together with information on safety and quality of cells and organs, while maintaining the dignity of donors and recipients.

In this book, we discuss different computational approaches for better, safe, and disease free transplantation and better chances of acceptance of graft. We discuss the application of computational tools in drug designing in brief.

While computational tools have been most important in improving human health and disease, they are also applied in understanding and decoding the highly diverse and immensely complex immune system of the invertebrates. We discuss the application of computational tools in understanding the immune system, cells, molecules, and pathways across the different invertebrate phyla, which enables our better understanding and has great potential in inferring at evolutionary advancements in life.

As the great Russian writer Anton Checkov said, “The task of a writer is not to solve the problem but to state the problem correctly.” With the glimpse of cutting edge modern day research, the idea of this book is to bring the information to students and the scientific community of the next generation and to nurture an inquisitive mind to understand nature’s mysteries in order to delve deeper into the mysteries of life hitherto unsolved.