دانلود کتاب ارتعاش کمی عملی و طیف الکترونیکی

The field of spectroscopy continues to advance in both hardware and software, and how it is applied in biological, pharmaceutical,medical, electronic, and environmental industries, among others.Much of the previous literature published in the 1980s and 1990s pertains to using quantitative spectroscopy in the agricultural and chemical industries. With the rapid improvement in computer speed, process analytical technology (PAT) applications rapidly became a “hot topic” at conferences. PAT continues to be an important area of focus for spectroscopists and engineers in the 21st century for improving product quality andmanufacturing cost savings. Chemometrics (i.e. principal component analysis) and machine learning for extracting information from large quantities of redundant and correlated data is inarguably one of the most widely used and published topics in spectroscopy today. The approach taken in this book is to offer a broad look at how and why spectroscopy is currently being used across multiple industries. The intent is to provide an instructional guide for developing methods that are not theoretical but practical to implement and fit for purpose. In many industrial sectors, quantitative spectroscopy procedures are used throughout the product’s life cycle, from the determination of contaminants in raw materials to problem-solving when product performance is compromised. Validated methods that adhere to FDA and ICH guidelines may need to be developed and implemented quickly to support rapidly changing business priorities. The traditional approach of creating a “training set” consisting of matrix-matched calibration standards may not always be needed or plausible. A good example is when light-based devices are used in longitudinal studies to measure the color change from a baseline. This book addresses real-world topics like short development time, training set design, wavelength selection strategies, and best practices for the lifecycle management of procedures, equipping you with the necessary tools to succeed in your projects. Part I captures years of knowledge gained by the authors when developing, validating, and implementing a quantitative procedure. It covers several quantitative approaches used in industry and academia to extract quantitative information from spectral data. The chapters are written from the perspective that many creative and useful spectroscopy procedures can be developed and used for many different purposes. This includes patent applications, clinical studies, and environmental testing both on Earth and in space. Many laboratories using spectroscopy instrumentation are implementing procedures for routine quality testing of samples using CFR 21 Part 11 compliant software as part of the initiative to improve laboratory efficiency. Part II of this book includes commercial ultraviolet, visible, near-infrared, mid-infrared, Raman, and SERS instrumentation applications. The applications were chosen to highlight important aspects of method development presented in Part I. The authors discuss how specific challenges were overcome to enhance method performance in various relevant applications. These include the measurement ofmicroplastics, petrochemicals, wine, pharmaceuticals, forensics, and illicit drugs. These practical examples are included to reassure you of your understanding and boost your confidence in applying the knowledge in your work. Part III of this book contains several “Vignettes” describing examples of problems solved while developing and implementing spectroscopy instrumentation for quantitative analysis. This valuable information is being shared, so developers can learn from these experienced authors and apply it in future applications. We aim to provide the reader with an understanding of managing quantitative spectroscopy projects. Part I of the book provides a mix of theory and experience-based knowledge on the various stages of building quantitative procedures. Part II and Part III are intended to broaden the readers’ understanding of how quantitative methods are applied and help to spark creativity for developing new quantitative spectroscopy procedures. While preparing these chapters, I gathered feedback fromvarious colleagues. I am grateful to the following individuals for their insightful reviews of different portions of the book: EmilW. Ciurczak, Pierre-Yves Sacré, Brian Rohrback, and Ryan Lerud. I also thank my creative colleague, Nicholas Minadeo, for enhancing the quality and resolution of many figures and images in this book. Finally, I am grateful for the fruitful discussions with Gary Ritchie, who identified two outstanding authors for this book.