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At Glasgow Royal Infirmary historically diabetes and clinical pharmacology were linked with specialists in each discipline contributing to one of the medical units in the provision of general medical care to the inhabitants of the east of Glasgow whilst delivering specialist expertise. A few miles north of the Royal Infirmary, Stobhill Hospital in its prime had physicians delivering care who were also delivering academic excellence in the Department of Materia Medica at the University of Glasgow. In 2011 the two hospitals in the northeast of Glasgow merged to provide in patient care on one site and in doing so brought together the prospect of having a combined Department of Diabetes, Endocrinology and Clinical Pharmacology. In addition to having a long-standing reputation for recruiting patients to commercial studies, the Royal Infirmary has strong links with the University of Glasgow, with senior academics continuing to provide both general and specialist patient care, and the University of Strathclyde Institute of Pharmacy and Biomedical Sciences, specifically around training independent pharmacy prescribers. Education and training have been hallmarks of the department and in 2008 a series of Drug Notes was established for Practical Diabetes, covering drugs used in those with diabetes but not necessarily ones for lowering blood glucose, encouraging trainees to be first authors. The series is still going, suggesting that an understanding of drugs is an essential part of being a healthcare provider with an interest in diabetes. Antidiabetic drugs were covered in two separate series for the British Journal of Cardiology, again with trainees aspiring to be specialists in diabetes and endocrinology being first authors and to consider clinical pharmacology as a key knowledge skill. With the emergence of new therapies for diabetes that are now providing benefits beyond glycaemic control, it seemed like the right time to bring together one definitive text that provides the prescriber with the background information and evidence that will help underpin their practice. We chose to ask colleagues in our department to contribute with the help of trainees working on a formula that has worked before but also because the clinical expertise within our department has specialists in both fields and contributed significantly to the Scottish Intercollegiate Guideline Network (SIGN) guideline for diabetes (SIGN116) but also to the Clinical Pharmacological update for type 2 diabetes in 2017 owing to the emergence of new classes of drugs to treat type 2 diabetes (SIGN154). We are grateful to colleagues and trainees in the Department of Diabetes, Endocrinology and Clinical Pharmacology for taking on the challenge of contributing to this book. As is often the case when taking on a task like this, it became incredibly time consuming, particularly as we neared completion, and therefore we owe a debt of gratitude to our families for their patience, understanding and support.