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The first edition of Chemistry for Pharmacy Students: General, Organic and Natural Product Chemistry was written to address the need for the right level and appropriate coverage of chemistry in any modern Pharmacy curricula. The first edition reflected on the changing face of Pharmacy profession and the evolving role of pharmacists in the modern healthcare systems, and was aimed at placing chemistry more in the context of medicines and patients. Since the publication in 2007, in subsequent years, the first edition has been translated into the Greek, Japanese and Portuguese languages, and has acclaimed huge acceptance and popularity among Pharmacy students, as well as among academics who teach chemistry in Pharmacy curricula all over the world. It has been over a decade since the publication of the first edition. We feel that it has now become necessary to compile a second edition, which should be a thoroughly revised and enhanced version of the first. The second edition will also cater for the chemistry requirements in any ‘Integrated Pharmacy Curricula’, where science in general is meant to be taught ‘not in isolation’, but together with, and as a part of, other practice and clinical elements of Pharmacy curricula. Whatever may be the structure and content of any Pharmacy curriculum, there will always be two fundamental aspects in it – medicines (drugs) and patients. Pharmacy began its journey as a medicine (drug)-focused science subject but, over the years, it has evolved as a more patient-focused subject. Irrespective of the focus, the need for chemistry knowledge and understanding in any Pharmacy curricula cannot be over-emphasized. We know that all drugs are chemicals. The ways any drug exerts its pharmacological actions and also toxicity in a patient are governed by a series of biochemical reactions. Therefore, chemistry knowledge and understanding are fundamental to any Pharmacy programme, which is essentially the study of various aspects of drugs, their applications in patients, patient care and overall treatment outcome. Like the first edition, this revised, reorganized and significantly enhanced second edition covers all core topics related to general, organic and natural product chemistry currently taught in Pharmacy undergraduate curricula in the UK, USA and various other developed countries, and relates these topics to drug molecules, their development and their fate once given to patients. While the second edition still provides a concise coverage of the essentials of general, organic and natural product chemistry into a manageable, affordable and student-friendly text, by concentrating purely on the basics of various topics without going into exhaustive detail or repetitive examples, the first chapter, which deals with various properties of drug molecules, has been significantly ‘beefed up’ in this second edition. Generally, the contents of the second edition are organized and dealt with in a similar way, to the first to ensure that the contents are suitable for year 1 (level 4) and year 2 (level 5) levels of most of the Pharmacy curricula. Theoretical aspects have been covered in the context of applications of these theories in relation to drug molecules, their discovery and developments.