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The summer after my first year in medical school, I visited a classmate at his home near the mental institution where his parents both worked. One afternoon, walking around the vast, open campus, we fell into conversation with a staff psychiatrist who told us about an interesting patient. This young woman had been admitted a few days earlier. While attending college nearby, she had suddenly become agitated—speaking rapidly and rushing in a frenzy from one activity to another. After she impulsively sold her nearly new Corvette for $500, her friends had brought her for evaluation. “Five hundred dollars!” exclaimed the psychiatrist. “That kind of thinking, that’s schizophrenia!” Now, my friend and I had had just enough exposure to mental health diagnosis to recognize that this young woman’s symptoms and course of illness were far more consistent with an episode of mania than with schizophrenia. We were too young and callow to challenge the diagnosis of an experienced clinician, but as we went on our way, we each expressed the fervent hope that this patient’s care would be less flawed than her assessment. For decades, the memory of that blown diagnosis has haunted me, in part because it is by no means unique in the annals of mental health. Indeed, it wasn’t until many years later that the first diagnostic manual to include specific criteria (DSM-III) was published. That book has since morphed into the enormous fifth edition of the Diagnostic and Statistical Manual of Mental Disorders, now a text revision (DSM-5-TR) published by the American Psychiatric Association. Anyone who evaluates and treats mental health patients must understand the latest edition of what has become the world standard for evaluation and diagnosis. But getting value from DSM- 5-TR requires a great deal of concentration. Written by a committee with the goal of providing standards for research as well as clinical practice in a variety of disciplines, it covers nearly every conceivable subject related to mental health. But you could come away from it not understanding how diagnostic criteria translate to an actual patient. I wrote DSM-5-TR Made Easy to make mental health diagnosis more accessible to clinicians from all mental health professions. In these pages, you will find descriptions of every mental disorder, with emphasis on those that occur in adults. With its careful use, today’s readers would be unlikely to mistake that young college student’s manic symptoms for schizophrenia.