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I conceptualized writing this book on drug manufacturing quality covering oral solid dosage (OSD), coatings technologies, and capsule flling (liquids and powders), with an emphasis on API safe handling and analytical method applications after spending over 30 years in drug manufacturing engineering, including aseptic liquid and lyoph­ilized parenteral drug vial fll/fnish, cartridge flling for injector applications, ster­ile preflled syringes, and ophthalmic bottle flling and copping. Quality by Design (QbD) dictates process preparations and compounding of drug formulations are key steps in transferring bulk product batches from beginning to end. These processes all require diligent care and technical know-how in transferring across process steps while maintaining clean and safe operations. Personnel fow and materials fow sepa­rations and consideration for movement have rigorous requirements to ensure against cross contamination and making a safe product. There are many guidelines that gov­ern all these processes defning specifc requirements. I wanted to put it all together in one accessible simplifed experience-based reference to reinforce knowledge of compliance regulations and processes, and provide an easy guide to follow. This book is important in providing a step-by-step understanding of what is required to engineer and manufacture drug products.