دانلود کتاب راهنمای تصویر رادیوتراپی با دقت بالا

Radiation therapy is one of the pillars of oncological treatment. As opposed to sur­gery, external beam radiation therapy requires the indirect depiction of the tumour and its surrounding structures both during the phase of treatment planning and dur­ing fractionated treatment. Historically, only pretreatment imaging was available and served as basis for the entire course of treatment, irrespective of anatomical changes caused, e.g. by tumour response or by patient’s weight loss.

During the last 15 years, advances in the field of image-guided radiotherapy have been dramatic. Anatomical and functional imaging is available prior to and during the course of treatment, occasionally even during the treatment fraction. Novel, tumour type-specific radionuclides have been developed for positron emission tomography (PET) and enable depiction of small tumour deposits, which would otherwise have been overlooked. Fast, highly precise radiation therapy techniques enable the treatment of small lesions. Linear accelerators integrated with magnetic resonance imaging (MRI) have revolutionized the field since they facilitate online real-time image-guided radiation dose delivery of moving soft-tissue targets. Herewith, safety margins compensating for repeat patient positioning and target motion can be reduced or even abolished, thus reducing dose to normal tissues and hopefully subsequent side effects.