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Minimum intervals – how to use them ;
When vaccine doses are given too close together , the body may have insufficient time to mount an immune response , and the vaccines efficacy cannot be assured.
It’s preferable to maintain the longer “recommended” interval whenever possible , with a few exceptions.
You should intentionally schedule patients at minimum intervals only in certain circumstances:
When catching up a child who starts his/ her immunizations late or more than one month behind schedule .
When a patient is scheduled to travel internationally.
When the patient is unlikely to return for recommended visits.

4 – day grace period ?
The ACIP has established one small exception to minimum intervals – “ the 4-day grace period – that allows vaccine doses administered up to four days before the minimum interval or age to be counted as valid. However , the 4-day grace period doesn’t apply in all situations. It shouldn’t be used when scheduling future vaccination visits . It also shouldn’t be applied to the 28-day interval recommended when live parenteral vaccines are not administered at the same visit or when giving rabies vaccine. The grace period should be used primarily when reviewing historical vaccination records.
N.B : In cases where the vaccine doses given less than 28 days apart are two doses of the same live vaccine in a series (e.g., 2 doses of MMR vaccine), not different vaccines , you don’t need to repeat the second dose if it was inadvertently administered within the 4-day “grace period” before day 28. If given more than 4 days earlier than day 28, the second dose should be repeated after the recommended minimum interval from the invalid dose.