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Health care professionals need to appreciate the interactions between medical conditions and social, economic, and environmental influences associated with the provision of pediatric care. New technologies and treatments improve morbidity, mortality, and the quality of life for children and their families, but the costs may exacerbate disparities in medical care. The challenge for pediatricians is to deliver care that is socially equitable; integrates psychosocial, cultural, and ethical issues into practice; and ensures that health care is available to all children.