دانلود کتاب درسی سفتی شریانی و همودینامیک ضربان دار در سلامت و بیماری

The field of arterial stiffness and pulsatile hemodynamics has significantly expanded over the last few decades. Increasingly, epidemiologists, clinicians, engineers, and biologists recognize the importance of large artery stiffening in various disease states. The role of large artery stiffness and pulsatile hemodynamics in cardiovascular aging is also widely recognized. However, there remains a gap between the biophysical and theoretical concepts and clinical practice. The aim of this textbook is to provide a comprehensive reference on arterial stiffness and pulsatile hemodynamics, covering the intersection of clinical, biologic, epidemiologic, and biophysical concepts. We intend for the audience of this book to be composed of clinical and basic science investigators interested in arterial stiffness, physicians and other healthcare providers, epidemiologists and biomedical engineers. Whereas excellent books are already available covering various aspects of this field, in many cases, these are highly specialized, are mathematically-oriented, are restricted to specific knowledge areas, or deal exclusively with clinical or biologic aspects without discussing hemodynamic mechanisms linking arterial stiffness and pulsatile hemodynamics with disease pathophysiology. Therefore, we intended to produce a book that introduces the interested reader to this field in relatively simple terms but at the same time covers, with reasonable depth, a broad range of relevant topics in biophysics, biology, epidemiology, and clinical medicine.