دانلود کتاب پارکینسونیسم و محیط زیست

The Use and Predictability of C. elegans as an Alternative and Complementary Model in Neurotoxicological Studies: Focus on the Dopaminergic System

Abstract Several alternative models have been used to create new studies on central nervous system (CNS) function. The benefits associated with these alternative approaches are time efficiency, reduced manpower, cost-effectiveness, and avoidance of ethical concerns on the use of higher vertebrates. In this regard, Caenorhabditis elegans (C. elegans), a small, free-living, soil nematode which uses bacteria as a food source, is being used to complement traditional experiments. Studies on worm genomes add new insights into the mechanisms of several neurological disorders and neuronal regeneration.