دانلود کتاب نحوه مدیریت اختلالات خونریزی اکتسابی

Bleeding event at the presentation or during the clinical course of a disease has often been an element of concern or emergency situation. Identifying the cause and managing it may require emergency diagnostic procedures and the need for specific counselling for appropriate diagnosis and symptom management. Knowledge of the main mechanisms underlying the coagulation process remains fundamental to correctly understanding the various moments in which these mechanisms can be altered and their consequences and therapeutic measures. Alongside the most well-known congenital diseases that are associated with haemorrhagic events, often already manifested in early childhood (haemophilia, von Willebrand disease,…), there are much more frequent clinical conditions that involve several branches of medicine across the board. It is now well appreciated how the use of antithrombotic or antiplatelet drugs can be complicated with haemorrhagic events, even severe, which require timely and individualized therapeutic interventions. The bleeding risk associated with relatively frequent diseases such as liver disease, disseminated intravascular coagulation and acute leukaemia must always be considered as one of the potential symptoms that can endanger the patient’s life. Trauma coagulopathy has received a lot of attention in recent years, identifying prognostic factors for a better clinical outcome, emphasizing the importance of urgent haemostatic treatment. Obviously, the haemorrhagic risk associated with more specific haematological situations, such as immune thrombocytopenia, acquired haemophilia and acquired von Willebrand disease, should not be overlooked, in which sometimes the diagnostic delay can weigh on the risk and unfortunate evolution for the haemorrhagic symptom. Finally, the management of the haemorrhagic event during pregnancy or childbirth can sometimes take on the connotations of a true emergency, which often requires a coordinated multidisciplinary approach. All these topics are dealt with in this book by colleagues of well-recognized value in the specific theme assigned to them. The chapters have above all tried to give a practical slant of management of the specific event to meet the needs not only of the colleagues involved but also of the young specialists in training in several branches of medicine. In thanking all the co-authors for their excellent contribution, our hope is that the text can be of useful and quick help in chaos of need.