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Decadent luxuries, dazzling technology, and startling new knowledge flood the senses and excite the imagination. What was the domain of science fiction less than a generation ago is now commonplace in many living rooms. Today, cable companies beam recently released movies to inches-thick televisions that hang on walls. All you have to do is press a few buttons on your remote control and your home is a cinema. And, with a couple of words to your virtual assistant, you can order a pizza that arrives in time for the start of the movie. In the field of healthcare, advancing knowledge of the immune system promises new cancer treatments that go to the source of the disease. Nanotechnology eventually will allow inconceivably small machines to clean out congested arteries like a plumber’s snake. And the human genome project begins to solve the mysteries behind countless inherited diseases. Sure, the world still has plenty of problems, but solutions for many of them lie on the horizon. Yet the World Health Organization paints a less optimistic picture. It estimates that on any given day, 264 million people worldwide suffer from depression. Over the course of a year, about 10 percent of the world’s population suffer from an episode of depression. Depression rates continue to increase. And most experts believe that the increase is real — not just a result of more people seeking help. Theories abound concerning the alarming increase in depression today. But regardless of the cause, this scourge robs its victims of happiness, joy, and the capacity to give and receive love. The good news is that more weapons exist for defeating depression than ever before. Clinicians have devised new psychotherapies that have been verified as effective in treating depression and preventing relapse. Medications, methods of stimulating key nerve centers, and other psychotherapies continue to be refined and developed. The majority of people no longer need to suffer with longstanding, intractable depression.