دانلود کتاب اطلس پوست‌شناسی نوجوانان

Acne vulgaris is a chronic inflammatory dermatosis with a complex interplay of four known pathogenic factors. There is follicular hyperkeratinization leading to follicular plugging in the pilosebaceous unit (comedones). This is coupled with an androgen-stimulated increase in sebum production and alteration of the sebum com
position. Proliferation of Cutibacterium acnes and an inflammatory response com
plete the tetrad.
Acne vulgaris is the most common skin disorder in the United States, and affects about 9% of the world population. The most common ages are adolescence and young adulthood. It affects approximately 85% of individuals aged 12–24 years and almost 50% of individuals aged 20–29 years.