دانلود کتاب کشف داروی ضد پیری بر اساس علائم بارز پیری

Population aging is a global phenomenon, indicating aging is already a major problem in most countries. However, no effective intervention was found to slow, stop, or reverse the aging process in humans. With this background, it was very timely to develop effective drugs for antiaging. However, considering various concepts and theories, there is actually no single mechanism that can perfectly explain the entire aging process. This indicates that various aspects should be considered at the same time in the process of drug development and design. As a result, this book includes chapters contributed by selected invited researchers. It provides a comprehensive thinking on the strategy of developing antiaging drugs in a multifaceted manner based on the currently known theories and evidence. The Antiaging Drug Discovery on the Basis of Hallmarks of Aging focuses on selected topics that are emerging and important new research on the promising strategies for antiaging drug discovery. The main area covered in this book comprises the general focus of most recent advances that may ultimately contribute to slowing or reversing the aging process and covers topics such as reactivation of telomerase, epigenetic approach, chaperone-related proteases controlling, stem cell-based therapies, and key signaling pathways associated with aging. This book summarizes the key points of each chapter according to hallmarks of aging and considers the practical implications for strategies of antiaging drug development. Collectively, we are confident that Antiaging Drug Discovery on the Basis of Hallmarks of Aging will be of great value in supporting the multidisciplinary efforts to understand many functions of the aging process, which will undoubtedly lead to the discovery of new pharmacological targets and therapeutic tools for the prevention and treatment of aging and aging-related disorders. Finally, we express our deepest thanks to the members for their incredible dedication and contributions. The excellence of this book is largely due to their efforts.