دانلود کتاب بیماری آلزایمر – زیست شناسی، بیوفیزیک و مدل های محاسباتی

Alzheimer’s disease (AD) is the leading cause of dementia and, unfortunately, is still incurable. About 47 million people worldwide are affected by AD or some other dementia and the social, emotional and financial implications of AD are immeasurable. As more and more people live longer due to improved healthcare around the world, the aging-associated neurodegenerative diseases are posing the greatest challenges to science and it is becoming imperative for us to understand the causes of these diseases, AD in particular, as it is the focus of this book, at molecular and cellular levels. Here we aim to summarize the main facts as we know them now so that we can develop a mechanistic understanding of dementia and AD in the later chapters; it is important to see the broader picture of the problem before we embark on our journey through this book: the fascinating biology and dynamics within and outside the neuron, the basic building block of brain.